Welcome

Group photo 2022

Welcome to the website of Cell Technology Laboratory (Muranaka's Lab), Department of Biotechnology, Osaka University. We are working at the leading edge of research on plant biotechnology to utilize cellular function and genetic resources of plants for social and industrial activities. Our findings will contribute to promote health, increase in food production and environmental conservation.

News

2022/8/19
A paper on Identification of key amino acid residues toward improving the catalytic activity and substrate specificity of plant-derived cytochrome P450 monooxygenases CYP716A subfamily enzyme for triterpenoid production in Saccharomyces cerevisiae by Jutapat Romsuk (D3) et al., has been published in Frontiers in Bioengineering and Biotechnology. [Link]
2022/8/18
A paper on High-yield bioactive triterpenoid production by heterologous expression in Nicotiana benthamiana using the Tsukuba system by Jutapat Romsuk (D3) et al., has been published in Frontiers in Plant Science. [Link]
2021/12/16
A paper on Comparative Analysis of NADPH-Cytochrome P450 Reductases From Legumes for Heterologous Production of Triterpenoids in Transgenic Saccharomyces cerevisiae by Pramesti Istiandari (D3) et al., has been published in Frontiers in Plant Science. [Link]
2021/06/25
A paper on Characterization of UDP-glucose dehydrogenase isoforms in the medicinal legume Glycyrrhiza uralensis by Ayumi Kawasaki (Guest Researcher) et al., has been published in Plant Biotechnology. [Link]
2021/02/23
A paper on Insights into the diversification of subclade IVa bHLH transcription factors in Fabaceae by Hayato Suzuki (D3) et al., has been published in BMC plant biology. [Link]
2021/01/13
A paper on Allylic hydroxylation activity is a source of saponin chemodiversity in the genus Glycyrrhiza by Much Zaenal Fanani (Guest Researcher) et al., has been published in Plant and Cell Physiology. [Link]
2020/11/20
A paper on The effect of nojirimycin on the transcriptome of germinating Orobanche minor seeds by Atsushi Okazawa (Guest Associate Prof.) et al., has been published in Journal of pesticide science. [Link]
2020/11/16
A paper on A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis by Soo Yeon Chung(D3) et al., has been published in Nature Communications. [Link] [News]
2020/06/25
A paper on Targeted genome editing in tetraploid potato through transient TALEN expression by Agrobacterium infection by Shuhei Yasumoto (Assistant Prof.) et al., has been published in Plant Biotechnology. [Link]
2020/04/20
A paper on the production of the bioactive plant‐derived triterpenoid morolic acid in engineered Saccharomyces cerevisiae, by Pisanee Srisawat (Guest Researcher) et al., has been published in Biotechnology and Bioengineering. [Link]
[This papaer was selected as an Editor's choice.]
2020/02/04
New leaflet of our research.Research
2019/11/27
A paper on the Structure-activity relationships of pentacyclic triterpenoids as inhibitors of cyclooxygenase and lipoxygenase enzymes by Nhu Ngoc Quynh Vo (D3) et al., has been published in Journal of Natural Products. [Link]
2019/11/01
A paper on the molecular basis of triterpene C-30 oxidases by Much Zaenal Fanani (D3) et al., has been published in Frontiers in Plant Science. [Link]
2019/10/01
A paper on Efficient genome engineering using Platinum TALEN in potato by Shuhei Yasumoto (Assistant Prof.) et al., has been published in Plant Biotechnology. [Link]
2019/08/16
A paper on the triterpenoid biosynthesis in a model legume plant Lotus japonicus, by Hayato Suzuki (D2) et al., has been published in Plant & Cell Physiology. [Link]
2019/06/22
A paper on the identification of oxidosqualene cyclases from the medicinal legume tree Bauhinia forficata, by Pisanee Srisawat (D3) et al., has been published in New Phytologist. [Link]
2019/05/28
A paper on the identification of TPSs related to sesquiterpenoid biosynthesis in Artemisia abrotanum, by Paskorn Muangphrom (Guest Researcher) et al., has been published in Phytochemistry. [Link]
2019/05/16
A paper on the identification of a glycosyltransferase related to glycyrrhizin biosynthesis in Glycyrrhiza uralensis, by Yuhta Nomura (Guest Researcher) et al., has been published in The Plant Journal. [Link]
2019/05/01
Shuhei Yasumoto has joined Muranaka laboratory as Assistant Professor. 2019/02/01
Ery Odette Fukushima (Associate Professor (Lecturer)) has moved out to Ikiam-Universidad Regional Amazónica (Ecuador). 2018/10/25
A paper on the identification of P450s related to triterpenoid biosynthesis in Avicennia marina, by Mitsuki Nakamura(M2) et al., has been published in Plant Biotechnology. [Link]
2018/06/26
A paper on the identificaion of the novel sesquiterpene synthase in Artemisia maritima, by Paskorn Muangphrom(Postdoctoral researcher) et al., has been published in Plant Biotechnology. [Link]
2018/06/26
A paper on the comparative analysis of CYP716A enzymes in yeast, by Hayato Suzuki(D1) and Ery O. Fukushima (Associate Prof. (Lecturer)) et al., has been published in Plant Biotechnology. [Link]
2018/03/30
A paper on the in planta phosphorylation of Arabidopsis HMG-CoA reductase, by Jekson Robertlee(Postdoctoral researcher) et al., has been published in Plant Biotechnology. [Link]
2018/02/27
A paper on the identification of the bHLH transcription factor regulating soyasaponin biosynthesis in Glycyrrhiza uralensis, by Keita Tamura (D3) et al., has been published in Plant and Cell Physiology. [Link]
2017/03/23
A paper on "chemical metabolic switching" to increase sesquiterpene content in plants, by Keiko Kobayashi (former researcher), Kanako Kobayashi (graduate) et al., has been published in Plant Biotechnology. [Link]
2017/03/23
A paper on the identification of P450s related to triterpenoid biosynthesis in Platycodon grandiflorus, by Keita Tamura (D2), Yuga Teranishi (M2) et al., has been published in Plant and Cell Physiology. [Link]
2017/03/6
A paper on the phosphorylation of Arabidopsis HMG-CoA reductase by AKIN10 protein, by Jekson Robertlee(D3) et al., has been published in FEBS Letters. [Link]
2017/01/05
A paper on the functional characterization of CYP716 family P450s of tomato, by Shuhei Yasumoto(D3) et al., has been published in Frontiers in Plant Science. [Link]