Establishing a sustainable society is one of the great modern concerns and the importance of an undegraded environment is well-recognized. Many chemicals have been released into the environment as a result of the great advances in synthetic chemistry that support our modern society.
However, despite much concern about possible harmful effects of these chemicals, their actual biological effects on humans and wildlife remain unclear. It is self evident that in order to develop and use these chemicals properly, understanding their effects on various organisms in the first place is essential. Our laboratory studies the biological responses elicited by environmental chemicals and is establishing a new system for evaluating how these chemicals affect humans and wildlife.
Genomics and Environment
In order to clarify the effects of chemicals on organisms, we applied ‘omics technologies. This approach enables us to classify many chemicals based on their biological effects and can predict how chemicals with an unknown biology will affect living organisms. This approach can lead to the identification of new biomarkers and the establishment of a new system for chemical evaluation.
Chemicals and Target Molecules
Once a chemical has been shown to affect an organism, it is important to understand which molecular targets mediate the chemical effect. Therefore, identifying the target(s) through which the chemical(s) act aids in understanding how they act and can also lead to the development of new sensors to detect the chemicals in the environment.
Model Organism from Ecosystem
Restricting our understanding of chemical action to their effects on mammals and other vertebrates is inconsistent with establishing a sustainable environment. Since the world’s waters are crucial for all life, we are particularly interested in aquatic organisms such as the water flea (Daphnia magna) as model organisms that represent ecosystem health. We apply molecular biological and ‘omics technologies to clarify the effects of chemicals on the environment. This “ecotoxicogenomic” approach is promising for evaluating chemical risks on ecosystems as well as finding useful and potentially unsuspected functions of the same chemicals.
- English version homepage was updated!
- D3 student, Kosuke Okamura's paper was accepted at Journal of Bioscience and Bioengineering.
- D3 student, Nur Izzatur binti Ismail's paper was accepted at PLoS One.
- D2 student, Maie Ahmed Elfaramawy's paper was accepted at Chemical Communications.
- New international student, Annisa Auliya Aksa joined the lab.
- Doctor's student Kerstin Toerner was graduated.
- D1 student, Nikko Adhitama's paper was accepted at Marine Environmental Research.
- Associate Professor Yasuhiko Kato's study about Long Non-Coding RNA was introduced at Osaka University Homepage ResOU.
- Assistant Professor Yasuhiko Kato's paper was accepted at Current Biology.
- Member's list was updated.
- Five new B4 students joined the lab.
- Doctor's students Nur Syafiqah Mohamad Ishak, Haruka Soga, and Hitoshi Kumagai were graduated.
- M1 student Hiroki Nakai and M2 student Christelle Alexa Garcia Perez were awarded best presenter at Mid Term Presentation of Biotechnology Department. link.
- Professor Tadashi Wada joined Watanabe Laboratory as invited professor.