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- Chiyo N., Seki H., Kanamoto T., Ueda H., Kojoma M., Muranaka T. (2024)
Glycyrrhizin Production in Licorice Hairy Roots Based on Metabolic Redirection of Triterpenoid Biosynthetic Pathway by Genome Editing.
Plant and Cell Physiology, 65(2): 185-198 [Link]

- Sakanishi M., Chung S. Y., Fujiwara K., Kojoma M., Muranaka T. Seki H. (2024)
Disruption of a licorice cellulose synthase-derived glycosyltransferase gene demonstrates its in planta role in soyasaponin biosynthesis.
Plant Cell Reports, 43: 15 [Link]



- Yasumoto S., Muranaka T. (2023)
Foreign DNA detection in genome-edited potatoes by high-throughput sequencing.
Scientific Reports, 13: 12246 [Link]

- Takahashi H., Abo C., Suzuki H., Romsuk J., Oi T., Yanagawa A., Gorai T., Tomisaki Y., Jitsui M., Shimamura S., Mori H., Kaga A., Ishimoto M., Seki H., Muranaka T., Nakazono M. (2023)
Triterpenoids in aerenchymatous phellem contribute to internal root aeration and waterlogging adaptability in soybeans.
New Phytologist, 239(3): 936-948 [Link]



- Rai A., Hirakawa H., Rai M., Shimizu Y., Shirasawa K., Kikuchi S., Seki H., Yamazaki M., Toyoda A., Isobe S., Muranaka T., Saito K (2022)
Chromosome-scale genome assembly of Glycyrrhiza uralensis revealed metabolic gene cluster centred specialized metabolites biosynthesis.
DNA Res., 29(6): 1-14 [Link]

- Romsuk J., Yasumoto S., Seki H., Fukushima E.O., Muranaka T. (2022)
Identification of key amino acid residues toward improving the catalytic activity and substrate specificity of plant-derived cytochrome P450 monooxygenases CYP716A subfamily enzyme for triterpenoid production in Saccharomyces cerevisiae.
Front. Bioeng. Biotechnol., 10: 955650 [Link]

- Romsuk J., Yasumoto S., Fukushima E.O., Miura K., Muranaka T., Seki H (2022)
High-yield bioactive triterpenoid production by heterologous expression in Nicotiana benthamiana using the Tsukuba system.
Front. Plant Sci., 13: 991909 [Link]


- 村中俊哉 (2022).
総論 「ゲノム編集で変わるこれからの作物育種」.
アグリバイオVol. 6(9): 6–7. [Link]

- 安本周平 (2022).
アグリバイオVol. 6(9): 12–16. [Link]

- 安本周平 (2022).
生物工学会誌 Vol. 100(6): 302–305. [Link]

- 關 光,CHUNG Soo Yeon,村中俊哉 (2022).
Regulation of Plant Growth & Development 57(2): 77-83

- CHUNG Soo Yeon,關 光,村中俊哉 (2022).
酵素工学ニュ-ス (88): 14-18



- Istiandari P., Yasumoto S., Srisawat P., Tamura K., Chikugo A., Suzuki H., Seki H., Fukushima EO., Muranaka T. (2021)
Comparative Analysis of NADPH-Cytochrome P450 Reductases From Legumes for Heterologous Production of Triterpenoids in Transgenic Saccharomyces cerevisiae.
Front Plant Sci., 16. [Link]

- Kawasaki A., Chikugo A., Tamura K., Seki H., Muranaka T. (2021)
Characterization of UDP-glucose dehydrogenase isoforms in the medicinal legume Glycyrrhiza uralensis.
Plant Biotechnol., 38, 205–218. [Link]

- Akiyama R., Nakayasu M., Umemoto N., Kato J., Kobayashi M., Lee HJ., Sugimoto Y., Iijima Y., Saito K., Muranaka T., Mizutani M. (2021)
Tomato E8 Encodes a C-27 Hydroxylase in Metabolic Detoxification of α-Tomatine during Fruit Ripening.
Plant Cell Physiol., 108, 81–92. [Link]

- Suzuki H., Seki H., Muranaka T. (2021)
Insights into the diversification of subclade IVa bHLH transcription factors in Fabaceae.
BMC Plant Biol., 21, 109. [Link]

- Akiyama R., Watanabe B., Nakayasu M., Lee H. J., Kato J., Umemoto N., Muranaka T., Saito K., Sugimoto Y., Mizutani M. (2021)
The biosynthetic pathway of potato solanidanes diverged from that of spirosolanes due to evolution of a dioxygenase.
Nat. Commun., 12, 1300. [Link]

- Fanani M. Z., Sawai S., Seki H., Ishimori M., Ohyama K., Fukushima E. O., Sudo H., Saito K., Muranaka T. (2021)
Allylic hydroxylation activity is a source of saponin chemodiversity in the genus Glycyrrhiza.
Plant Cell Physiol., 62, 262–271. [Link]


- 關光, Chung Soo Yeong, 村中俊哉 (2021).
ファルマシアVol. 57(8): 710–714. [Link]

- 村中俊哉, 關光 (2021).
化学 Vol. 76(6): 553–555. [Link]

- 關光, 鈴木隼人 (2021).
生物工学会誌 Vol. 99(5): 246–249. [Link]

- Chung Soo Yeong, 關光, 村中俊哉 (2021).
バイオサイエンスとインダストリー Vol. 79(3): 205–209. [Link]



- Okazawa A., Wakabayashi T., Muranaka T., Sugimoto Y., Ohta D. (2020)
The effect of nojirimycin on the transcriptome of germinating Orobanche minor seeds.
J. Pestic. Sci., 45, 230–237. [Link]

- Chung S.Y., Seki H., Fujisawa Y., Shimoda Y., Hiraga S., Nomura Y., Saito K., Ishimoto M., Muranaka, T. (2020)
A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis.
Nat. Commun., 11, 5664. [Link]

- Yasumoto S., Sawai S., Lee H.J., Mizutani M., Saito K., Umemoto N., Muranaka T. (2020)
Targeted genome editing in tetraploid potato through transient TALEN expression by Agrobacterium infection.
Plant Biotechnol., 37, 205–211. [Link]

- Srisawat P., Yasumoto S., Fukushima E.O., Robertlee J., Seki H., Muranaka T. (2020)
Production of the bioactive plant‐derived triterpenoid morolic acid in engineered Saccharomyces cerevisiae.
Biotechnol. Bioeng., 117: 2198–2208. [Link]


- Tabei Y., Muranaka T. (2020)
Preface to the special issue “Technology in tissue culture toward horizon of plant biotechnology”.
Plant Biotechnol., 37, 117–120. [Link]


-關光, 北村実紗子, 世戸口貴宏, 鈴木隼人 (2020).
大豆たん白質研究 Vol. 23: 46–51. [Link]



- Munakata R., Takemura T., Tatsumi K., Moriyoshi E., Yanagihara K., Sugiyama A., Suzuki H., Seki H., Muranaka H., Kawano N., Yoshimatsu K., Kawahara N., Grosjean J., Bourgaud F., Hehn A., Yazaki K. (2019)
Isolation of Artemisia capillaris membrane-bound di-prenyltransferase for phenylpropanoids and redesign of artepillin C in yeast.
Communications Biol., 2: 384. [Link]

- Vo N.N., Nomura Y, Muranaka T., Fukushima E.O. (2019)
Structure-activity relationships of pentacyclic triterpenoids as inhibitors of cyclooxygenase and lipoxygenase enzymes.
J. Nat. Prod., 82, 3311–3320. [Link]

- Fanani M.Z., Fukushima E.O., Sawai S., Tang J., Ishimori M., Sudo H., Ohyama K., Seki H., Saito K., Muranaka T. (2019)
Molecular basis of C-30 product regioselectivity of legume oxidases involved in high-value triterpenoid biosynthesis.
Front. Plant Sci., 10: 1520. [Link]

- Yasumoto S., Umemoto N., Lee H.J., Nakayasu M., Sawai S., Sakuma T., Yamamoto T., Mizutani M., Saito K., Muranaka T. (2019)
Efficient genome engineering using Platinum TALEN in potato.
Plant Biotechnol., 36, 167–173. [Link]

- Suzuki H., Fukushima E.O., Shimizu Y., Seki H., Fujisawa Y., Ishimoto M., Osakabe K., Osakabe Y., Muranaka T. (2019)
Lotus japonicus triterpenoid profile and characterization of the CYP716A51 and LjCYP93E1 genes involved in their biosynthesis in planta.
Plant Cell Physiol., 60: 2496–2509. [Link]

- Srisawat P., Fukushima E.O., Yasumoto S., Robertlee J., Suzuki H., Seki H., Muranaka T. (2019)
Identification of oxidosqualene cyclases from the medicinal legume tree Bauhinia forficata: a step toward discovering preponderant α‐amyrin‐producing activity.
New Phytol., 224, 352–366. [Link]

- Muangphrom P., Misaki M., Suzuki M., Shimomura M., Suzuki H., Seki H., Muranaka T. (2019)
Identification and characterization of (+)-α-bisabolol and 7-epi-silphiperfol-5-ene synthases from Artemisia abrotanum.
Phytochemistry, 164, 144–153. [Link]

- Nomura M., Seki H., Suzuki T., Ohyama K., Mizutani M., Kaku T., Tamura K., Ono E., Horikawa M., Sudo H., Hayashi H., Saito K., Muranaka T. (2019)
Functional specialization of UDP‐glycosyltransferase 73P12 in licorice to produce a sweet triterpenoid saponin, glycyrrhizin.
Plant J., 99, 1127–1143. [Link]


- 關光, 高上馬希重, 村中俊哉 (2019)
アグリバイオVol. 3(11): 1038–1041. [Link]



- Nakamura M., Linh T.M., Lien L.Q., Suzuki H., Mai N.C., Giang V.H., Tamura K., Thanh N.V., Suzuki H., Misaki R., Muranaka T., Ban N.K., Fujiyama K., Seki H. (2018)
Transcriptome sequencing and identification of cytochrome P450 monooxygenases involved in the biosynthesis of maslinic acid and corosolic acid in Avicennia marina.
Plant Biotechnol., 35, 341–348. [Link]

- Takagi K., Yano R., Tochigi S., Fujisawa Y., Tsuchinaga H., Takahashi Y., Takada Y., Koga A., Anai T., Tsukamoto C., Seki H., Muranaka T., Ishimoto M. (2018)
Genetic and functional characterization of Sg-4 glycosyltransferase involved in the formation of sugar chain structure at the C-3 position of soybean saponins.
Phytochemistry, 156, 96–105. [Link]

- Kusano H., Ohnuma M., Mutsuro-Aoki H., Asahi T., Ichinosawa D., Onodera H., Asano K., Noda T., Horie T., Fukumoto K., Kihara M., Teramura H., Yazaki K., Umemoto N., Muranaka T., Shimada H. (2018)
Establishment of a modified CRISPR/Cas9 system with increased mutagenesis frequency using the translational enhancer dMac3 and multiple guide RNAs in potato.
Sci. Rep., 8, 13753. [Link]

- Nakayasu M., Akiyama R., Lee H. J., Osakabe K., Osakabe Y., Watanabe B., Sugimoto Y., Umemoto N., Saito K., Muranaka T., Mizutani M. (2018)
Generation of α-solanine-free hairy roots of potato by CRISPR/Cas9 mediated genome editing of the St16DOX gene.
Plant Physiol. Biochem., 131, 70–77. [Link]

- Suzuki H., Fukushima E.O., Umemoto N., Ohyama K., Seki H., Muranaka T. (2018)
Comparative analysis of CYP716A subfamily enzymes for the heterologous production of C-28 oxidized triterpenoids in transgenic yeast.
Plant Biotechnol., 35, 131–139. [Link]

- Muangphrom P., Seki H., Matsumoto S., Nishiwaki M., Fukushima E.O.,Muranaka T. (2018)
Identification and characterization of a novel sesquiterpene synthase, 4-amorphen-11-ol synthase, from Artemisia maritima.
Plant Biotechnol., 35, 113–121. [Link]

- Robertlee J., Kobayashi K., Tang J., Suzuki M., Muranaka T. (2018)
Evidence that the Arabidopsis thaliana 3-hydroxy-3-methylglutaryl-CoA reductase 1 is phosphorylated at Ser577 in planta.
Plant Biotechnol., 35, 1–7. [Link]

- Yano R., Takagi K., Tochigi S., Fujisawa Y., Nomura Y., Tsuchinaga H., Takahashi Y., Takada Y., Koga A., Anai T., Tsukamoto C., Seki H., Muranaka T., Ishimoto M. (2018)
Isolation and Characterization of the Soybean Sg-3 Gene that is Involved in Genetic Variation in Sugar Chain Composition at the C-3 Position in Soyasaponins.
Plant Cell Physiol., 59, 792–805. [Link]

- Tamura K., Yoshida K., Hiraoka Y., Sakaguchi D., Chikugo A., Mochida K., Kojoma M., Mitsuda N., Saito K., Muranaka T., Seki H. (2018)
The basic helix-loop-helix transcription factor GubHLH3 positively regulates soyasaponin biosynthetic genes in Glycyrrhiza uralensis.
Plant Cell Physiol., 59, 783–796. [Link]


- 鈴木秀幸, 關光, 刑部祐里子, 刑部敬史, 村中俊哉 (2018)
18章 オーム科学と植物バイオテクノロジー.
基礎から学ぶ植物代謝生化学, 羊土社 (東京), 301–314.[Link]

- Seki H., Tamura K., Muranaka T. (2018)
Plant-derived isoprenoid sweeteners: recent progress in biosynthetic gene discovery and perspectives on microbial production.
Biosci. Biotechnol. Biochem., 82, 927–934. [Link]



- Nakayasu M., Umemoto N., Ohyama K., Fujimoto Y., Lee H.J., Watanabe B., Muranaka T., Saito K., Sugimoto Y., Mizutani M.(2017)
A dioxygenase catalyzes steroid 16α-hydroxylation in steroidal glycoalkaloid biosynthesis.
Plant Physiol., 175, 120–133. [Link]

- Kobayashi K., Kobayashi K., Yamaguchi H., Inoue Miyagi Y., Takagi K., Fushihara K., Seki H., Suzuki M., Nagata N., Muranaka T. (2017)
Platform for “chemical metabolic switching” to increase sesquiterpene content in plants.
Plant Biotechnol., 34, 65–69. [Link]

- Tamura K., Teranishi Y., Ueda S., Suzuki H., Kawano N., Yoshimatsu K., Saito K., Kawahara N., Muranaka T., Seki H. (2017)
Cytochrome P450 monooxygenase CYP716A141 is a unique β-amyrin C-16β oxidase involved in triterpenoid saponin biosynthesis in Platycodon grandiflorus.
Plant Cell Physiol., 58, 874–884. [Link]

- Robertlee J., Kobayashi K., Suzuki M., Muranaka T. (2017)
AKIN10, a representative Arabidopsis SNF1-related protein kinase 1 (SnRK1), phosphorylates and downregulates plant HMG-CoA reductase.
FEBS Lett., 591, 1159–1166. [Link]

- Yasumoto S., Seki H., Shimizu Y., Fukushima E.O., Muranaka T. (2017)
Functional characterization of CYP716 family P450 enzymes in triterpenoid biosynthesis in tomato.
Front. Plant Sci., 8:21. [Link]

- Tamura K., Seki H., Suzuki H., Kojoma M., Saito K., Muranaka T. (2017)
CYP716A179 functions as a triterpene C-28 oxidase in tissue-cultured stolons of Glycyrrhiza uralensis.
Plant Cell Rep., 36, 437–445. [Link]

- Vo N.N., Fukushima E.O., Muranaka T. (2017)
Structure and hemolytic activity relationships of triterpenoid saponins and sapogenins.
J. Nat. Med., 71, 50–58. [Link]


- Muangphrom P., Seki H., Muranaka T. (2017)
Revealing the catalytic residues of amorpha-4,11-diene synthase (ADS): new insight for engineering terpene synthases.
Biotarget, 1, 19. [Link]



- Mochida K., Sakurai T., Seki H., Yoshida T., Takahagi K., Sawai S., Uchiyama H., Muranaka T., Saito K. (2016)
Draft genome assembly and annotation of Glycyrrhiza uralensis, a medicinal legume.
Plant J., 89, 181–194. [Link]

- Umemoto N., Nakayasu M., Ohyama K., Yotsu-Yamashita M., Mizutani M., Seki H., Saito K., Muranaka T. (2016)
Two cytochrome P450 monooxygenases catalyze early hydroxylation steps in the potato steroid glycoalkaloid biosynthetic pathway.
Plant Physiol., 171, 2458–2467. [Link]

- Muangphrom P., Seki H., Suzuki M., Komori A., Nishiwaki M., Mikawa R., Fukushima E.O., Muranaka T. (2016)
Functional analysis of amorpha-4,11-diene synthase (ADS) homologs from non-artemisinin-producing Artemisia species: The discovery of novel koidzumiol and (+)-α-bisabolol synthases.
Plant Cell Physiol., 57, 1678–1688. [Link]

- Tsukagoshi Y., Ohyama K., Seki H., Akashi T., Muranaka T., Suzuki H., Fujimoto Y. (2016)
Functional characterization of CYP71D443, a cytochrome P450 catalyzing C-22 hydroxylation in the 20-hydroxyecdysone biosynthesis of Ajuga hairy roots.
Phytochemistry, 127, 23–28. [Link]

- Tsukagoshi Y., Suzuki H., Seki H., Muranaka T., Ohyama K., Fujimoto Y. (2016)
Ajuga Δ24-sterol reductase catalyzes the direct reductive conversion of 24-methylenecholesterol to campesterol.
J. Biol. Chem., 291, 8189–8198. [Link]

- Yasumoto S., Fukushima E.O., Seki H., Muranaka T. (2016)
Novel triterpene oxidizing activity of Arabidopsis thaliana CYP716A subfamily enzymes.
FEBS Lett., 590, 533–540. [Link]


- 安本周平, 村中俊哉 (2016)
All Aboutゲノム編集“革命的技術”はいかにして私たちの研究・医療・産業を変えるのか?, 羊土社 (東京), 158–163.

- 安本周平, 村中俊哉 (2016)
ゲノム編集入門 –ZFN・TALEN・CRISPR-Cas9–, 羊土社 (東京), 160–183.

- 關光, 田村啓太, 村中俊哉 (2016)
Foods Food Ingredients J. Jpn., 221, 225–231.

- Muangphrom P., Seki H., Fukushima E.O., Muranaka T. (2016)
Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites.
J. Nat. Med., 70, 318–334. [Link]



- Khakimov B., Kuzina-Poulsen V., Erthmann P.Ø., Fukushima E.O., Augustin J.M., Olsen C.E., Scholtalbers J., Volpin H., Andersen S.B., Hauser T.P., Muranaka T., Bak S. (2015)
Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana.
Plant J., 84, 478–490. [Link]

- Wakabayashi T., Benesh J., Yasumoto S., Akashi T., Aoki T., Harada K., Muranaka S., Bamba T., Fukusaki E., Takeuchi Y., Yoneyama K., Muranaka T., Sugimoto Y., Okazawa A. (2015)
Planteose as a storage carbohydrate required for early stage of germination of Orobanche minor and its metabolism as a possible target for selective control.
J. Exp. Bot., 66, 3085–3097. [Link]

- Nakayasu M., Kawasaki T., Lee H.J., Sugimoto Y., Onjo M., Muranaka T., Mizutani M. (2015)
Identification of furostanol glycoside 26-O-β-glucosidase involved in steroidal saponin biosynthesis from Dioscorea esculenta.
Plant Biotechnol., 32, 299–308. [Link]


- 安本周平, 關光, 刑部祐里子, 刑部敬史, 村中俊哉 (2015)
論文だけではわからない ゲノム編集成功の秘訣Q&A TALEN、CRISPR/Cas9の極意, 実験医学別冊, 羊土社 (東京), 228–243.

- 安本周平, 關光, 村中俊哉 (2015)
進化するゲノム編集技術, エヌ・ティー・エス (東京) 235–241.

- Seki H., Tamura K., Muranaka T. (2015)
P450s and UGTs: Key players in the structural diversity of triterpenoid saponins.
Plant Cell Physiol., 56, 1463–1471. [Link]



- Tamura M., Tsuji Y., Kusunose T., Okazawa A., Kamimura N., Mori T., Nakabayashi R., Hishiyama S., Fukuhara Y., Hara H., Sato-Izawa K., Muranaka T., Saito K., Katayama Y., Fukuda M., Masai E., Kajita S. (2014)
Successful expression of a novel bacterial gene for pinoresinol reductase and its effect on lignan biosynthesis in transgenic Arabidopsis thaliana.
Appl. Microbiol. Biotechnol., 98, 8165–8177. [Link]

- Sawai S., Ohyama K., Yasumoto S., Seki H., Sakuma T., Yamamoto T., Takebayashi Y., Kojima M., Sakakibara H., Aoki T., Muranaka T., Saito K., Umemoto N. (2014)
Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in Potato.
Plant Cell, 26, 3763–3774. [Link]

- Muangphrom P., Suzuki M., Seki H., Fukushima E.O., Muranaka T. (2014)
Functional analysis of orthologous artemisinic aldehyde Δ11(13)-reductase reveals potential artemisinin-producing activity in non-artemisinin-producing Artemisia absinthium.
Plant Biotechnol., 31, 483–491. [Link]

- Okazawa A., Kusunose T., Ono E., Kim H.J., Satake H., Shimizu B., Mizutani M., Seki H., Muranaka T. (2014)
Glucosyltransferase activity of Arabidopsis UGT71C1 towards pinoresinol and lariciresinol.
Plant Biotechnol., 31, 561–566. [Link]

- Choi H., Ohyama K., Kim Y.Y., Jin J.Y., Lee S.B., Yamaoka Y., Muranaka T., Suh M.C., Fujioka S., Lee Y. (2014)
The role of Arabidopsis ABCG9 and ABCG31 ATP binding cassette transporters in Pollen Fitness and the deposition of steryl glycosides on the pollen coat.
Plant Cell, 26, 310–324. [Link]


- 安本周平, 關光, 村中俊哉 (2014)
生物工学会誌, 92, 533–555. [Link]

- Fukushima E.O., Seki H., Muranaka T. (2014)
Plant cytochrome P450s in triterpenoid biosynthesis: Diversity and application to combinatorial biosynthesis.
Fifty years of Cytochrome P450 research, Springer Japan, 125–133.

- Fukushima E.O., Seki H., Muranaka T. (2014)
Heterologous expression of triterpene biosynthetic genes in yeast and subsequent metabolite identification through GC-MS.
Plant Isoprenoids, Methods Mol. Biol., 1153, 235–243.

- 關光, 田村啓太, 村中俊哉 (2014)
薬用植物・生薬の最前線 –国内栽培技術から品質評価, 製品開発まで–, シーエムシー出版 (東京), 132–139.

- 安本周平, 關光, 村中俊哉 (2014)
今すぐ始めるゲノム編集, 実験医学別冊, 羊土社 (東京), 189–199.



- Ramilowski J.A., Sawai S., Seki H., Mochida K., Yoshida T., Sakurai T., Muranaka T., Saito K., Daub C.O. (2013)
Glycyrrhiza uralensis transcriptome landscape and study of phytochemicals.
Plant Cell Physiol., 54, 697–710. [Link]

- Fukushima E.O., Seki H., Sawai S., Suzuki M., Ohyama K., Saito K., Muranaka T. (2013)
Combinatorial biosynthesis of legume natural and rare triterpenoids in engineered yeast.
Plant Cell Physiol., 54, 740–749. [Link]

- Komori A., Suzuki M., Seki H., Nishizawa T., Meyer J.J., Shimizu H., Yokoyama S., Muranaka T. (2013)
Comparative functional analysis of CYP71AV1 natural variants reveals an important residue for the successive oxidation of amorpha-4,11-diene.
FEBS Lett., 587, 278–284. [Link]

- Hata N., Hayashi Y., Ono E., Satake H., Kobayashi A., Muranaka T., Okazawa A. (2013)
Differences in plant growth and leaf sesamin content of the lignan-rich sesame variety 'Gomazou' under continuous light of different wavelengths.
Plant Biotechnol., 30, 1–8. [Link]

- Shirasawa K., Ishii K., Kim C., Ban T., Suzuki M., Ito T., Muranaka T., Kobayashi M., Nagata N., Isobe S., Tabata S. (2013)
Development of Capsicum EST-SSR markers for species identification and in silico mapping onto the tomato genome sequence.
Mol. Breed., 31, 101–110. [Link]


- Muranaka T., Saito K. (2013)
Phytochemical genomics on the way.
Plant Cell Physiol., 54, 645–646. [Link]

- 福島エリオデット, 關光, 村中俊哉 (2013)
生物工学会誌 91, 337–341. [Link]



- Go Y.S., Lee S.B., Kim H.J., Kim J., Park H.Y., Kim J.K., Shibata K., Yokota T., Ohyama K., Muranaka T., Arseniyadis S., Suh M.C. (2012)
Identification of marneral synthase, which is critical for growth and development in Arabidopsis.
Plant J., 72, 791–804. [Link]

- Hirao T., Okazawa A., Harada K., Kobayashi A., Muranaka T., Hirata K. (2012)
Green leaf volatiles enhance methyl jasmonate response in Arabidopsis.
J. Biosci. Bioeng., 144, 540–545. [Link]

- Itoh K., Nakamura K., Aoyama T., Matsuba R., Kakimoto T., Murakami M., Yamanaka R., Muranaka T., Sakamaki H., Takido T. (2012)
Photobiocatalyzed asymmetric reduction of ketones using Chlorella sp. MK201.
Biotechnol. Lett., 34, 2083–2086. [Link]

- Heintz D., Gallien S., Compagnon V., Berna A., Suzuki M., Yoshida S., Muranaka T., Van Dorsselaer A., Schaeffer C., Bach T.J., Schaller H. (2012)
Phosphoproteome exploration reveals a reformatting of cellular processes in response to low sterol biosynthetic capacity in Arabidopsis.
J. Proteome Res., 11, 1228–1239. [Link]

- Kunii M., Kitahama Y., Fukushima E.O., Seki H., Muranaka T., Yoshida Y., Aoyama Y. (2012)
β-amyrin oxidation by Oat CYP51H10 expressed heterologously in yeast cells: The first example of CYP51-dependent metabolism other than the 14-demethylation of sterol precursors.
Biol. Pharm. Bull., 35, 801–804. [Link]


- Muranaka T., Ohyama K. (2012)
Functional analysis of HMG-CoA reductase and oxidosqualene cyclases in Arabidopsis.
Isoprenoid Synthesis in Plants and Microorganisms, Springer New York, 465–474.

- 關光, 村中俊哉 (2012)
バイオサイエンスとインダストリー, 70, 192–195.



- Fukushima E.O., Seki H., Ohyama K., Ono E., Umemoto N., Mizutani M., Saito K., Muranaka T. (2011)
CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.
Plant Cell Physiol., 52, 2050–2061. [Link]

- Tang J., Ohyama K., Kawaura K., Hashinokuchi H., Kamiya Y., Suzuki M., Muranaka T., Ogihara Y. (2011)
A new insight into application for barley chromosome addition lines of common wheat: achievement of stigmasterol accumulation.
Plant Physiol., 157, 1555–1567. [Link]

- Seki H., Sawai S., Ohyama K., Mizutani M., Ohnishi T., Sudo H., Fukushima E.O., Akashi T., Aoki T., Saito K., Muranaka T. (2011)
Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin.
Plant Cell, 23, 4112–4123. [Link]


- Muranaka T. (2011)
Plant gateway vectors for RNAi as a tool for functional genomic studies.
Methods Mol. Biol., 744, 27–35.

- 關光, 村中俊哉 (2011)
生物工学会誌, 89, 656–659. [Link]

- 澤井学, 關光, 大山清, 村中俊哉, 斉藤和季 (2011)
Bio Industry, 28, 6–12.



- Rydén A.M., Ruyter-Spira C., Quax W.J., Osada H., Muranaka T., Kayser O., Bouwmeester H. (2010)
The molecular cloning of dihydroartemisinic aldehyde reductase and its implication in artemisinin biosynthesis in Artemisia annua.
Planta Med., 76, 1778–1783. [Link]

- Uchida H., Yamashita H., Anai T., Muranaka T., Ohyama K. (2010)
Agrobacterium-mediated transformation of Euphorbia tirucalli callus.
Biosci. Biotechnol. Biochem., 74, 851–853. [Link]

- Kim O.T., Kim S.H., Ohyama K., Muranaka T., Choi Y.E., Lee H.Y., Kim M.Y., Hwang B. (2010)
Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase.
Plant Cell Rep., 29, 403–411. [Link]

- Tang J., Kobayashi K., Suzuki M., Matsumoto S., Muranaka T. (2010)
The mitochondrial PPR protein LOVASTATIN INSENSITIVE 1 plays regulatory roles in cytosolic and plastidial isoprenoid biosynthesis through RNA editing.
Plant J., 61, 456–466. [Link]

- Kojoma M., Ohyama K., Seki H., Hiraoka Y., Asazu S.-N., Sawa S., Sekizaki H., Yoshida S., Muranaka T. (2010)
In vitro proliferation and triterpenoid characteristics of licorice (Glycyrrhiza uralensis Fischer, Leguminosae) stolons.
Plant Biotechnol., 27, 59–66. [Link]

- Uchida H., Ohyama K., Suzuki M., Yamashita H., Muranaka T., Ohyama K. (2010)
Triterpenoid levels are reduced during Euphorbia tirucalli L. callus formation.
Plant Biotechnol., 27, 105–109. [Link]

- Mano Y., Nemoto K., Suzuki M., Seki H., Fujii I., Muranaka T. (2010)
The AMI1 gene family: indole-3-acetamide hydrolase functions in auxin biosynthesis in plants.
J. Exp. Bot., 61, 25–32. [Link]



- Nemoto K., Hara M., Suzuki M., Seki H., Oka A., Muranaka T., Mano Y. (2009)
Function of the aux and rol genes of the Ri plasmid in plant cell division in vitro.
Plant Signal Behav., 4, 1145–1147. [Link]

- Nemoto K., Hara M., Goto S., Kasai K., Seki H., Suzuki M., Oka A., Muranaka T., Mano Y. (2009)
The aux1 gene of the Ri plasmid is sufficient to confer auxin autotrophy in tobacco BY-2 cells.
J. Plant Physiol., 166, 729–738. [Link]

- Uchida H., Yamashita H., Kajikawa M., Ohyama K., Nakayachi O., Sugiyama R., Yamato K.T., Muranaka T., Fukuzawa H., Takemura M., Ohyama K. (2009)
Cloning and characterization of a squalene synthase gene from a petroleum plant, Euphorbia tirucalli L.
Planta, 229, 1243–1252. [Link]

- Suzuki M., Nakagawa S., Kamide Y., Kobayashi K., Ohyama K., Hashinokuchi H., Kiuchi R., Saito K., Muranaka T., Nagata N. (2009)
Complete blockage of the mevalonate pathway results in male gametophyte lethality.
J. Exp. Bot., 60, 2055–2064. [Link]

- Nemoto K., Hara M., Suzuki M., Seki H., Muranaka T., Mano Y. (2009)
The NtAMI1 gene functions in cell division of tobacco BY-2 cells in the presence of indole-3-acetamide.
FEBS Lett., 583, 487–492. [Link]

- Ohyama K., Suzuki M., Kikuchi J., Saito K., Muranaka T. (2009)
Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis.
Proc. Natl. Acad. Sci. USA, 106, 725–730. [Link]

- Ziaratnia S.M., Ohyama K., Hussein A.A., Muranaka T., Lall N., Kunert K.J., Meyer J.J. (2009)
Isolation and identification of a novel chlorophenol from a cell suspension culture of Helichrysum aureonitens.
Chem. Pharm. Bull., 57, 1282–1283. [Link]

- Hoson T., Matsumoto S., Soga K., Wakabayashi K., Hashimoto T., Sonobe S., Muranaka T., Kamisaka S., Kamada M., Omori K., Ishioka N., Shimazu T. (2009)
Growth and cell wall properties in hypocotyls of Arabidopsis tua6 mutant under microgravity conditions in space.
Biol. Sci. Sp., 23, 71–76. [Link]

- Sudo H., Seki H., Sakurai N., Suzuki H., Shibata D., Toyoda A., Totoki Y., Sakaki Y., Iida O., Shibata T., Kojoma M., Muranaka T., Saito K. (2009)
Expressed sequence tags from rhizomes of Glycyrrhiza uralensis.
Plant Biotechnol., 26, 105–107. [Link]


- 關光, 大山清, 村中俊哉 (2009)
薬用植物甘草のグリチルリチン生合成遺伝子の発見 -組み換え酵母で生合成中間体の生産に成功-
化学と生物, 47, 714–716. [Link]



- Babiychuk E., Bouvier-Navé P., Compagnon V., Suzuki M., Muranaka T., Van Montagu M., Kushnir S., Schaller H. (2008)
Albinism and cell viability in cycloartenol synthase deficient Arabidopsis.
Plant Signal Behav., 3, 978–980. [Link]

- Seki H., Ohyama K., Sawai S., Mizutani M., Ohnishi T., Sudo H., Akashi T., Aoki T., Saito K., Muranaka T. (2008)
Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin.
Proc. Natl. Acad. Sci. USA, 105, 14204–14209. [Link]

- Zhang H., Ohyama K., Boudet J., Chen Z., Yang J., Zhang M., Muranaka T., Maurel C., Zhu J.K., Gong Z. (2008)
Dolichol biosynthesis and its effects on the unfolded protein response and abiotic stress resistance in Arabidopsis.
Plant Cell, 20, 1879–1898. [Link]

- Ziaratnia S.M., Hussein A.A., Kiyoshi O., Muranaka T., Kunert K.J., Meyer J.J.M. (2008)
A novel phenolic compound and an alternative biosynthetic pathway for flavonoids in Helichrysum aureonitens.
South African J. Bot. , 74, 384. [Link]

- Babiychuk E., Bouvier-Navé P., Compagnon V., Suzuki M., Muranaka T., Van Montagu M., Kushnir S., Schaller H. (2008)
Allelic mutant series reveal distinct functions for Arabidopsis cycloartenol synthase 1 in cell viability and plastid biogenesis.
Proc. Natl. Acad. Sci. USA, 105, 3163–3168. [Link]

- Asakura Y., Seki H., Muranaka T., Yamamura Y., Kurosaki F. (2008)
Enhanced secretory activity of Atropa belladonna hairy root culture over-expressing ADP-ribosylation factor gene.
Biol. Pharm. Bull., 31, 1465–1468. [Link]

- Suzuki M., Kobayashi K., Nagata N., Matsuda O., Iba K., Yoshida S., Muranaka T. (2008)
Novel root culture system using a recessive mutant with a rooty phenotype.
Plant Biotechnol., 25, 197–200. [Link]

- Seki H., Ohyama K., Nishizawa T., Yoshida Y., Muranaka T. (2008)
The “all-in-one” rol-type binary vectors as a tool for functional genomic studies using hairy roots.
Plant Biotechnol., 25, 347–355. [Link]



- Sasaki K., Saito T., Lämsä M., Oksman-Caldentey K.M., Suzuki M., Ohyama K., Muranaka T., Ohara K., Yazaki K. (2007)
Plants utilize isoprene emission as a thermotolerance mechanism.
Plant Cell Physiol., 48, 1254–1262. [Link]

- Kohara A., Nakajima C., Yoshida S., Muranaka T. (2007)
Characterization and engineering of glycosyltransferases responsible for steroid saponin biosynthesis in Solanaceous plants.
Phytochemistry, 68, 478–486. [Link]

- Kobayashi K., Suzuki M., Tang J., Nagata N., Ohyama K., Seki H., Kiuchi R., Kaneko Y., Nakazawa M., Matsui M., Matsumoto S., Yoshida S., Muranaka T. (2007)
Lovastatin insensitive 1, a novel pentatricopeptide repeat protein, is a potential regulatory factor of isoprenoid biosynthesis in Arabidopsis.
Plant Cell Physiol., 48, 322–331. [Link]

- Hoson T., Matsumoto S., Soga K., Wakabayashi K., Hashimoto T., Sonobe S., Muranaka T., Kamisaka S., Kamada M., Omori K., Ishioka N., Shimazu T. (2007)
The outline and significance of the resist wall experiment: Role of microtubule-membrane-cell wall continuum in gravity resistance in plants.
Biol. Sci. Sp., 21, 56–61. [Link]

- Ohyama K., Suzuki M., Masuda K., Yoshida S., Muranaka T. (2007)
Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis.
Chem. Pharm. Bull., 55, 1518–1521. [Link]


- Suzuki M., Muranaka T. (2007)
Molecular genetics of plant sterol backbone synthesis.
Lipids, 42, 47–54. [Link]



- Rahman L., Kitamura Y., Yamaguchi J., Mukai M., Akiyama K., Yamamoto H., Muranaka T., Ikenaga T. (2006)
Exogenous plant H6H but not bacterial HCHL gene is expressed in Duboisia leichhardtii hairy roots and affects tropane alkaloid production.
Enzyme Microb. Technol., 39, 1183–1189. [Link]

- Kojoma M., Seki H., Yoshida S., Muranaka T. (2006)
DNA polymorphisms in the tetrahydrocannabinolic acid (THCA) synthase gene in "drug-type" and "fiber-type" Cannabis sativa L.
Forensic Sci. Int., 159, 132–140. [Link]

- Suzuki M., Xiang T., Ohyama K., Seki H., Saito K., Muranaka T., Hayashi H., Katsube Y., Kushiro T., Shibuya M., Ebizuka Y. (2006)
Lanosterol synthase in dicotyledonous plants.
Plant Cell Physiol., 47, 565–571. [Link]



- Seki H., Nishizawa T., Tanaka N., Niwa Y., Yoshida S., Muranaka T. (2005)
Hairy root-activation tagging: a high-throughput system for activation tagging in transformed hairy roots.
Plant Mol. Biol., 59, 793–807. [Link]

- Kohara A., Nakajima C., Hashimoto K., Ikenaga T., Tanaka H., Shoyama Y., Yoshida S., Muranaka T. (2005)
A novel glucosyltransferase involved in steroid saponin biosynthesis in Solanum aculeatissimum.
Plant Mol. Biol., 57, 225–239. [Link]



- Suzuki M., Kamide Y., Nagata N., Seki H., Ohyama K., Kato H., Masuda K., Sato S., Kato T., Tabata S., Yoshida S., Muranaka T. (2004)
Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels.
Plant J., 37, 750–761. [Link]



- Suzuki M., Nagata N., Kamide Y., Yoshida S., Muranaka T. (2003)
The study of the mechanism of cell elongation using an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase.
Advanced Research on Plant Lipids, Springer Netherlands, 249–252.

- Nagata N., Suzuki M., Yoshida S., Muranaka T. (2003)
Action of mevalonic acid-derived isoprenoids in Arabidopsis.
Advanced Research on Plant Lipids, Springer Netherlands, 245–248.



- Nagata N., Suzuki M., Yoshida S., Muranaka T. (2002)
Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway.
Planta, 216, 345–350. [Link]

- Putalun W., Tanaka H., Muranaka T., Shoyama Y. (2002)
Determination of aculeatisides based on immunoassay using a polyclonal antibody against aculeatiside A.
Analyst, 127, 1328–1332. [Link]